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Psychedelics: Exploring the Brain | David Erritzøe | TEDxAarhus

  • Published on Jun 5, 2017
  • In his talk, David introduces us to psychedelics and his research on how they might be a key to solve the problems with mental illness.

    David Erritzoe is a medical doctor and clinical psychiatrist. In the years after finishing medical school at Copenhagen University in 2001, he trained under Professor Marc Laruelle at Columbia University in New York City, and later under Professor Gitte Moos Knudsen in the Center for Integrated Molecular Brain Imaging (CIMBI) in Copenhagen. The subject was molecular and functional brain imaging.

    In 2009 he completed his PhD on serotonergic neurotransmission and subsequently moved to Imperial College London to conduct post-doc addiction research under the mentorship of Professors Anne Lingford-Hughes and David Nutt. At Imperial, David has been involved in psychopharmacological and brain imaging research, mainly investigating dopaminergic and opioid neurotransmission in addiction. In addition to that, he is part of a research programme together with Professor Nutt and Dr Carhart-Harris conducting research in neurobiology and the treatment potential of MDMA and classic psychedelics.

    This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

Comments • 128

  • Anthony Dunn
    Anthony Dunn 4 years ago +137

    Remember, if you're gonna try psychedelics, make sure you're not gonna be around strangers or anything else you might be uncomfortable with when really high. Do your research and have a kickass, potentially life changing time.

    • catgirl journey
      catgirl journey 3 months ago +1

      go be in nature
      and don’t look in mirrors!

    • Scott Jones
      Scott Jones 4 years ago +1

      Anthony Dunn sweet profile pic

  • HuduYooVudu
    HuduYooVudu 4 years ago +32

    I've been getting interested in Psychadelics after dropping LSD about a month ago. I'm glad this along with Marijuana has been a hot topic among people around the world. Everyone is taking a step back like "Hold on. The government has been lying about weed for several decades now, now what other beneficial Schedule 1 drugs have they been lying about"

    • Alice Lascaux
      Alice Lascaux 2 years ago

      @Solidarity Time and oh no! A clipboard!

    • Julien Eric
      Julien Eric 2 years ago +2

      @Solidarity Time We'll never know

    • Solidarity Time
      Solidarity Time 2 years ago +1

      Hey! Have you tripped in the year it's been since you commented this?

  • Jop Mens
    Jop Mens 4 years ago +5

    I think part of the therapeutic effects are from downregulation of 5-HT2A. Lower activity of this receptor is associated with lowered stress, better sleep and many other things. I agree though that the experience itself can also be transformative, priming, and one of the things which apparently can be helpful is the breaking of cramped and rusty thought patterns. However this potential can probably be utilized for very positive but also negative change depending on the quality of the experience, which much like meditation is a way of brainwashing without necessarily the negative connotation.
    An LSD experience actually bears a lot of similarity to a week-long meditation retreat in my experience. I think this should serve as a hint to do research on similar therapeutic effects meditation has found to have with psychedelics to see which ones can be confirmed.

    • Wakko Warner
      Wakko Warner 3 years ago +1

      Jop Mens meditation takes a long time, some people need the quick action of psychedelics to get the benefits so that they can then be taught how to meditate to maintain the benefits.

    • Mr. Mojo Risin
      Mr. Mojo Risin 4 years ago +2

      Jop Mens I believe you’re right, psychedelics seem to break unhealthy thought patterns. So does meditation, but meditation requires a lot of self control which some people with these problems do not have. I think a profound psychedelic experience paired with meditation is the answer.

  • Mulec emrun
    Mulec emrun 4 years ago +5

    He is absolutely right that we should monitor psychedelics administration in clients in order to get desired outcomes, if otherwise it would be similar to destruction and split of personality! so they should be administered by expert and not by individuals! A very serious Ted Talk!

    • Alice Lascaux
      Alice Lascaux 2 years ago +1

      oh for the love of all that's good and holy!!
      Willl you science type people quit rambling on about the rest of us being blithering, cowering idiots!!!

    • Wakko Warner
      Wakko Warner 3 years ago +3

      Muhammad Imran Ghallow if they didn’t follow safety procedures they’d be members of the CIA and not doctors

  • Extraneus
    Extraneus 4 years ago +3

    Started using MMJ and learned a lot about myself. Back on antidepressants and starting to feel more depressed than ever. Been in a major depressive episode for 6-7 months now.

    • Alice Lascaux
      Alice Lascaux 2 years ago +1

      @Jimmy's Tractor shut up science type person! You are out of the equation now

    • 61percentodicarica
      61percentodicarica 2 years ago +1

      Try and learn how to lucid dream.
      It helped A LOT a person I know (who stopped taking prescription drugs, after consulting his therapist, because they had a very mild effect compared to dreams)

      Because of him I started getting into lucid dreaming as well - life changing experience, for everybody.

    • callum matthew
      callum matthew 3 years ago

      humanyoda it is. its mild, but it is.

    • Jimmy's Tractor
      Jimmy's Tractor 3 years ago

      They do work for some people. Cure isn't such a clear word anymore, many people can live a normal life as long as they take a certain drug til they die of something unrelated. Food only cures starvation if you take it every day. Some ailments like cancer need to be cured every 5-10 years for some people.

    • humanyoda
      humanyoda 4 years ago

      MMJ isn't a psychedelic.

  • zbanch123
    zbanch123 4 years ago +1

    Theun Mares books may help in such situations also. They contain technics to cope with painful memories.

  • Vickie Lawson
    Vickie Lawson 10 months ago +1

    That cathedral at 5:57 is absolutely stunningly beautiful.

  • sanjuansteve
    sanjuansteve 4 years ago +9

    I think I may have a near total cross hallucinogenic tolerance. I've only had (other than weed) LSD twice and mushrooms twice, but I predicted the 1st time with LSD would have little affect and so took 3 tabs of what were said to be double dose (600 mu) tabs and they had quite little affect on me. My next time with LSD and 2 times with mushrooms were all also supposedly similarly heavy doses, all from totally different sources and all with nearly no affects. I look forward to really diving in to this mushroom season coming next month and my first chance with ayahuasca, but I have zero faith that they have the capacity at virtually any dose to confuse my brain. lol Someone should add me to some study, if remotely, because I think it's a rare thing and so it would be interesting data.

    • Graham Anderson
      Graham Anderson Year ago

      @Marco Jonesmagical comment

    • Wakko Warner
      Wakko Warner 3 years ago

      I was the same way as you, but when I vaporized 100mg dmt or a high dose (over 5 grams dried power) of shrooms always makes me trip balls. LSD doesn’t do much for me.

    • Marco Jones
      Marco Jones 4 years ago +14

      I think it's working better than you think. You're actually tripping right now this is a video about skin care routines no one knows what you're talking about and I'm your dog

    • sanjuansteve
      sanjuansteve 4 years ago

      No, I haven't, but this weekend is a road trip for mushrooms in season in the wild here now.

    • Rat Cam
      Rat Cam 4 years ago +1

      Just wandering as this was 2 months ago, have you tried Ayahuasca yet? If you have, what was the effect on you?

  • Alex Ullrich
    Alex Ullrich Year ago +10

    Wow Mark Ruffalo really got into this role

  • Loose uNit
    Loose uNit 7 months ago


  • Cthulhu Man
    Cthulhu Man 4 years ago +26

    Can i sign up for this experiment?

  • tiluriso
    tiluriso 2 years ago +7

    9:15 - OK, but one does get a child-like-curiosity-feeling while on LSD - I did, many times.

  • Vanfl
    Vanfl 4 months ago +1

    What if magic mushrooms and other psychedelics are illegal bc our ancestors succeeded so much with these "drugs" and were getting ahead of their time bc of these items so the government wanted to make all the "big changes" and are selfish about growing as a country and or species?

  • Lauren Briscoe
    Lauren Briscoe 9 months ago

    Please know psychedelics can trigger psychosis can mean terrrifying mental images, flashbacks, being unable to speak or eat or drink, deranged behavior, violence, inability to work and function, loss of intelligence, creative skills, cognitive skills, extreme depression, loss of identity, inability to parent, suicide, delusions, paranoia, auditory and visual hallucinations, loss of job, hospitalization, and possibly homelessness. The depression afterwards can be severe and take years to recover from. Many people have suffered. I’m not exaggerating.

  • Guilherme Pimentel
    Guilherme Pimentel 3 years ago +27

    Are we gonna ignore the fact that his boots are cool

    • Vickie Lawson
      Vickie Lawson 10 months ago +1

      Are we gonna ignore the fact that his pant legs are messed up?

    • Fedor Kinaya
      Fedor Kinaya 2 years ago +1

      It is was very important to him that we notice his boots haha. Great talk though

  • Montesa
    Montesa 4 months ago +1

    So, if you suffer from severe depression you have to keep taking Psychedelics every few months?

    • Smackpoint GSPs
      Smackpoint GSPs 3 months ago +1

      @Montesa yes, for many people, one dose is all it takes.
      I have had great success using 2gms per session, currently every 3 months.
      For me, I'm working on CPTSD from child abuse, depression, anxiety, neuropathy and dissociative identify disorder. I'm using it as I pull the mental threads on my childhood, to try to change the way I react to things. So for me it is an ongoing process. But after the very first dose, that internal, negative voice was silenced and I no longer thought about suicide, which was a serious daily struggle for me.
      It has, and is changing my life.

    • Smackpoint GSPs
      Smackpoint GSPs 3 months ago

      @Montesa absolutely

    • Montesa
      Montesa 3 months ago

      @Smackpoint GSPs @Smackpoint GSPs - you mean you can just take one dose & it can cure your depression permanently? How big a dose would that be?

    • Montesa
      Montesa 3 months ago

      @Smackpoint GSPs @Smackpoint GSPs - Thanks for the information. Any chance we could talk?

    • Smackpoint GSPs
      Smackpoint GSPs 3 months ago

      For many it's a one and done fix. For some, it's helpful to "top up" occasionally, be that at 3,6 or 12 month intervals. It all comes down to the individual and their own issues.
      For myself, I top up every so often as I have been using it to work through complex mental and physical issues. But each time the interval gets longer and longer. And it will not be a long term necessity, like the other meds I have been on for almost 30 years.

  • Random Rangoon
    Random Rangoon Year ago +4

    It was closed down because no money is made from a cure.
    Too many closed minded people that carry a lifetime of stigma as well
    I think it's that simple.

  • 30k Subscribers Without Video

    imagine if ADAM & EVE tooks Magic Mushroom instead of apple...

    • Sterling Riebling
      Sterling Riebling 6 months ago

      As you can recall the psychedelic issue WAS there in Eden.”do not eat of the fruit of knowledge, or you will become as we are” - Yahweh

    • Vickie Lawson
      Vickie Lawson 10 months ago +1

      @Jonas Bové Apes are sentient (able to think and feel things). You mean sapient (ability to know things and reason with that knowledge).

    • Sally Masterson-Matychowiak
      Sally Masterson-Matychowiak 11 months ago

      that would have been awesome!

    • Konstantin Tarkus
      Konstantin Tarkus Year ago +2

      Apple was never mentioned in Adam & Eve story.

    • Avante Levine
      Avante Levine Year ago

      What if the mushroom was the apple...? That's why we try to find our way back.

  • Sedunk
    Sedunk 2 years ago +3

    Love this stuff but just can’t get down with this guy.

  • David Gennaro
    David Gennaro 4 years ago +4

    Who did the sound on this?

  • 30k Subscribers Without Video

    how i wish Magic Mushroom is planted at Garden of Eden long time ago. not an apple.

  • full stop
    full stop 2 years ago +2

    It is so deceptive. You uphold it like a saviour.

  • elokubano
    elokubano 3 years ago +5

    Harsh comment loading: 'How to turn an endlessly fascinating topic into a coma inducing talk'

    • Alice Lascaux
      Alice Lascaux 2 years ago +1

      Well done! I love it! Are you from the UK by chance? ( The sense of humour)

  • Gama
    Gama 2 years ago +3

    Earnin app easily most hated ads on RU-clip

  • Prasen Waikar
    Prasen Waikar 4 years ago +2

    this video is osum

  • humanyoda
    humanyoda 4 years ago +1

    If David weren't a psychiatrist focused on drugs, he'd know that there are transformational psychological processes that allow people to quickly let go of their depressions, phobias, anxieties, etc. He'd also be less confused about how psychedelics do what they do.

    • SuperGroob
      SuperGroob 2 years ago +2

      Please enlighten us.... I would love to hear more about these transformational psychological processes. Seriously.

    • Patrick Foster
      Patrick Foster 3 years ago +5

      humanyoda "let go of their depression quickly". Are you kidding? If psychiatry offered a quick cure for depression how is it their are millions of Americans suffering from it currently? I can tell you that SSRI's and blabbering on a couch do NOTHING for actual major depression. In reality they have nothing useful to offer the patient who suffers from depression, not to mention "treatment resistant" depression.

  • MajorTom 642
    MajorTom 642 4 years ago +1

    As interesting as this guy diction is painful.
    Had to stop...

  • Zzid
    Zzid 4 years ago +10

    This guy shouldn't talk in front of an audience.

    • Jonas Bové
      Jonas Bové Month ago

      @French fry His first language is Danish - you are correct. :)

    • French fry
      French fry 3 months ago

      I don't think English is his first language.

    • Duka Oliveira
      Duka Oliveira 3 years ago

      Of course, you should be talking in front of an audience, why not?

    • Millian Avertis
      Millian Avertis 3 years ago +11

      Most Danes speak pretty fluent English, at least the younger generations. This guy just has a really thick accent, if you can't understand what he's saying that's on you.
      Perhaps you should work on yourself instead of projecting.

    • Mr. Mojo Risin
      Mr. Mojo Risin 4 years ago +14

      In the description it says he studied at the Copenhagen university, so I would believe English is not his first language. Give him a break